Studies Provide Strongest Evidence To Date For Causative Role of Inflammation...
Two large new meta-analyses published in the Lancet provide the first strong evidence demonstrating a cause-and-effect relationship between a specific inflammatory protein and the development of...
View ArticleNHLBI Announces 7000 Patient Trial Testing Inflammation Hypothesis
The National Heart, Lung, and Blood Institute (NHLBI) has announced the launch of a large clinical trial testing the inflammation hypothesis. Paul Ridker is the principal investigator of the trial,...
View ArticleColchicine Found Effective in Acute Pericarditis
Although colchicine has been shown to be beneficial in patients with recurrent pericarditis, which is thought to have a large inflammatory component related to an immune response, until now its...
View ArticleNews From Our ‘Statin Civilization': High-Dose Statins Found To Reduce Gum...
In addition to their well-known benefits in heart disease, high-dose statins appear to reduce gum inflammation caused by periodontal disease, a new report published in the Journal of the American...
View ArticleCANTOS Validates Role Of Inflammation In Heart Disease
–Modest treatment effect of canakinumab may limit clinical role in heart disease, but strong anti-cancer signal sparks interest. Despite questions about its clinical importance, the CANTOS trial is...
View ArticleImaging Studies Offer New Insights Into Inflammation In CV Disease
–Preliminary evidence that colchicine may reduce coronary plaque. Interest in inflammation has risen considerably in the cardiology community as a result of the recent CANTOS trial. The large 10,000...
View ArticleCANTOS Substudy Shows Major Role For Inflammation
–Large reductions in hsCRP appeared to foretell improved outcomes. ANAHEIM — An important CANTOS trial substudy bolsters evidence that inflammation plays an independent role in cardiovascular disease...
View ArticleNIH Halts Large Cardiovascular Inflammation Reduction (CIRT) Trial
The NHLBI has put an early stop to the large Cardiovascular Inflammation Reduction (CIRT) Trial. The NHLBI action was based on a recommendation from the trial’s Data and Safety Monitoring Board. The...
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