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Studies Provide Strongest Evidence To Date For Causative Role of Inflammation...

Two large new meta-analyses published in the Lancet provide the first strong evidence demonstrating a cause-and-effect relationship between a specific inflammatory protein and the development of...

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NHLBI Announces 7000 Patient Trial Testing Inflammation Hypothesis

The National Heart, Lung, and Blood Institute (NHLBI) has announced the launch of a large  clinical trial testing the inflammation hypothesis. Paul Ridker is the principal investigator of the trial,...

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Colchicine Found Effective in Acute Pericarditis

Although colchicine has been shown to be beneficial in patients with recurrent pericarditis, which is thought to have a large inflammatory component related to an immune response, until now its...

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News From Our ‘Statin Civilization': High-Dose Statins Found To Reduce Gum...

In addition to their well-known benefits in heart disease, high-dose statins appear to reduce gum inflammation caused by periodontal disease, a new report published in the Journal of the American...

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CANTOS Validates Role Of Inflammation In Heart Disease

–Modest treatment effect of canakinumab may limit clinical role in heart disease, but strong anti-cancer signal sparks interest. Despite questions about its clinical importance, the CANTOS trial is...

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Imaging Studies Offer New Insights Into Inflammation In CV Disease

–Preliminary evidence that colchicine may reduce coronary plaque. Interest in inflammation has risen considerably in the cardiology community as a result of the recent CANTOS trial. The large 10,000...

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CANTOS Substudy Shows Major Role For Inflammation

–Large reductions in hsCRP appeared to foretell improved outcomes. ANAHEIM — An important CANTOS trial substudy bolsters evidence that inflammation plays an independent role in cardiovascular disease...

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NIH Halts Large Cardiovascular Inflammation Reduction (CIRT) Trial

The NHLBI has put an early stop to the large Cardiovascular Inflammation Reduction (CIRT) Trial. The NHLBI action was based on a recommendation from the trial’s Data and Safety Monitoring Board. The...

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